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7 Although all were healthy individuals, clinical characteristics (eg, age, gender, body mass index and blood pressure), as well as the vendor-specific software used for longitudinal strain analysis, may explain the variation in LV GLS. GLS Values Vary by Vendor, Gender and Age Plana et al. J Am Soc Echocardiogr 2014;27:911-39 GE Philips Toshiba Normal Strain Values Threshold for Abnormal • Global Longitudinal Strain Normal GLS:> -17% Borderline GLS: between -17% and -15% Clearly Abnormal GLS: < -15% Think of GLS in absolute values (I Prefer to Forget the – sign) Gorcsan J. 2017 Global Strain Must Relate to Ejection Fraction Strain gradient remained unchanged in age decades. Conclusion: Ageing shows an independent effect on GLS, LSsubendo, and, particularly on, LSsubepi. Our data also provide normal reference values of layer-specific longitudinal strain for age decades.

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Normal values for SR using STE are less well studied and therefore there is no clear clinical consensus for these values. Normal resting values of between 1.0/s and 1.4/s (SD 0.5–0.6/s) have been suggested by leading experts for longitudinal deformation .

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To obtain GLS, all strain values were averaged [15]. We considered normal value of GLS − 19.7% based on previously reported values for GE Medical System [16]. What is Normal? Global Longitudinal Strain GLS: -15.7 to -21.1%, mean -19.7% N = 2,597 Yingchoncharoen…Marwick et al. JASE 2013;26:185 GLS Values Vary by Vendor, Gender and Age Plana et al. J Am Soc Echocardiogr 2014;27:911-39 GE Philips Toshiba Normal Strain Values Threshold for Abnormal • Global Longitudinal Strain Normal GLS:> -17% Borderline GLS: between -17% and -15% Clearly Abnormal GLS: < -15% 2013-02-01 · The search identified 2,597 subjects from 24 studies. Reported normal values of GLS varied from −15.9% to −22.1% (mean, −19.7%; 95% CI, −20.4% to −18.9%).

Diagnostic accuracy of STE The data extracted from the selected studies are GLS Normal Values According to a meta-analysis GLS values changed from -15.9% to -22.1% (11) but a value above -20%±2%SD is generally accepted as normal (12). Smiseth et al.
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Normal global circumferential strain varied from −20.9% to −27.8% (mean, −23.3%; 95% CI, −24.6% to −22.1%).

Global Longitudinal Strain GLS: -15.7 to -21.1%, mean -19.7% N = 2,597 Yingchoncharoen…Marwick et al. JASE 2013;26:185 GLS Values Vary by Vendor, Gender and Age Plana et al. J Am Soc Echocardiogr 2014;27:911-39 GE Philips Toshiba Normal Strain Values Threshold for Abnormal • Global Longitudinal Strain Normal GLS:> -17% Borderline GLS: between -17% and -15% Clearly Abnormal GLS: < -15% 2013-02-01 · The search identified 2,597 subjects from 24 studies. Reported normal values of GLS varied from −15.9% to −22.1% (mean, −19.7%; 95% CI, −20.4% to −18.9%).
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Anderson Beginners Guide to Strain - American Society of Echocardiography 2018-12-01 · In separate multiple linear regression analyses, the effect of age on GLS, LSsubendo, and LSsubepi remained significant even after adjusting for clinical and echocardiographic confounders. Strain gradient remained unchanged in age decades. Conclusion: Ageing shows an independent effect on GLS, LSsubendo, and, particularly on, LSsubepi. Our data also provide normal reference values of layer-specific longitudinal strain for age decades.